Airway Choices in the Era of Many Choices

 

In the beginning, there was awake blind nasal tracheal intubation, a brutal and often unsuccessful technique that thankfully disappeared when non-anesthesiologists gained access to paralytics. The primary tool for emergency airway management then became the traditional laryngoscope, a device little improved since the 1940s, until the advent of video laryngoscopy in the early 2000s which changed everything.

The age of VL was ushered in by the 2001 Glidescope, which simultaneously introduced two technologies: video (putting a camera at the end of the blade and projecting the image onto a screen), and hyperangulated geometry (blades with a much steeper curve that are designed not to move the tongue out of the way, but to advance around the tongue). It took us a decade to figure out that video was a transformational advance, but not hyperangulated geometry, which is a trade-off compared to conventional standard geometry (Macintosh or Miller) blades. But because they were introduced together, in the same revolutionary device, another decade has passed and there is still much confusion about how these technologies fit together.

Direct laryngoscopy uses a blade to push the tongue out of the way, establishing a direct line of site between the eye and the glottis; intubation is carried out by looking in the mouth. Video laryngoscopy uses a blade with a camera at the end; once the blade is positioned, the operator intubates looking at the screen. VL can employ either SG or HA blades. HAVL, which uses a blade that goes around the tongue, requires that the operator look at the screen. SGVL uses blades that move the tongue out of the way, allowing the operator to look in the mouth and perform DL (usually more difficult), or look at the screen and perform VL. Traditional laryngoscopy is using an old-school 1943 laryngoscope, which of course can only do DL.

The hopefully over VL vs. DL debate

For many years, there was a raging debate about VL vs. DL, but this has become less relevant with the rise of VL systems that incorporate hot-swappable SG and HA blades, allowing providers to switch between HAVL and SGVL in seconds. Because you can perform DL using an SGVL blade in the same way you would perform TL, SGVL is direct and video, SGVL contains TL, and now that we can instantly flip between SGVL and HAVL, it has become obvious to most (I hope) that there is no longer a role for TL. I still see pockets of enthusiasm for the 1943 laryngoscope, but this seems to me usually a demonstration of machismo similar to how an aged cardiologist recently condescended to me for relying on ultrasound to diagnose tamponade. All airway providers must be competent in DL, but only because video is not always available.

The real debate: SGVL vs. HAVL

The question now is which video blade to reach for. Practitioners who are highly skilled at either SGVL or HAVL will successfully intubate nearly everyone; both techniques are excellent.

HA blades produce an excellent view of the glottis almost every time with very little practice, and can get good views when SG blades can’t. This is a very important advantage, especially for folks who intubate infrequently, because seeing the cords calms you down, and you do a better job when you’re calm. HAVL requires less force, head/neck movement, and tissue displacement, which is an advantage in neck immobility, limited mouth opening, or an oral lesion that would bleed if disturbed. However, the fantastic view easily obtained with HAVL comes at the price of more difficult tube delivery, because the view from the camera points up, while the trachea points down. This can be overcome with maneuvers designed to flatten the angle between camera-view and trachea, but these maneuvers involve degrading your view, and are therefore against your instincts, and also don’t apply to SGVL or DL, where you want to optimize your view.

SGVL is quicker than HAVL, because tube delivery is (literally) straightforward, and this advantage is powerfully magnified by a bougie, which can be used with HAVL but is simpler with SG. Similarly, suction is easier to apply with an SG blade, and this can make a big difference in heavily soiled airways. The view-optimizing goals of SGVL are intuitive and work with your instincts, and the SGVL skillset applies directly to DL/TL, which is not true of HAVL.

The Era of Single-Use Flexible Endoscopy

Flexible endoscopes,  often called fiberoptic bronchoscopes, are immensely powerful airway tools that until recently have been available in a small minority of emergency settings, because the conventional devices are expensive, fragile, and require a sterilization process that often doesn’t fit into EM workflows. The development of single-use, disposable endoscopes has brought this technology downstairs, and these devices are now available from several vendors.

Most emergency providers have little experience with flexible endoscopy, but they are not hard to use and a reasonable degree of proficiency can be acquired in a single mannequin session. The gadgets are often referred to as fiberoptic, though most of them no longer use fiberoptic technology, and often referred to as bronchoscopes, though they are rarely used for bronchoscopy in the ED.

Their classic use is as a primary intubation modality using meticulous local anesthesia, in a patient who is fully or nearly fully awake, and breathing normally. Topicalized Awake Intubation (TAI) is a core skill for anesthesiology but not always easily applied to emergency practice because it requires time and some degree of patient cooperation, as well as materials and topicalization skills not always present. It is still a skill that should be taught and practiced in EM training, because it is the safest way to intubate patients with a high degree of known or predicted difficulty, and absolutely can be performed successfully in many emergency scenarios.  An alternative breathing intubation technique that provides some (not all) of the safety of TAI but is much easier to deploy in the ED is the use of dissociative dose ketamine without a paralytic (KOBI). More discussion around the merits and demerits of these two techniques can be found here and here.

Most ED patients, however, are (appropriately) intubated using a paralytic, and flexible endoscopy, now more available in the ED, is perhaps even more important as part of an RSI-based airway strategy.  Using an endoscope by itself (often through the nose) is the traditional way to execute TAI, and this can work well in other techniques where the patient continues to breathe (such as KOBI), but if used after a paralytic, flexible endoscopic intubation is best accomplished in combination with either a video laryngoscope (where you can go fast) or laryngeal mask (where you can continue to ventilate during the procedure).

I got my hands on a disposable flexible endoscope years ago and described an ED Double Setup that incorporates 2-provider video laryngoscopy + flexible endoscopy; a single-provider variation on this procedure using a channeled VL was published by Sowers & Kovacs.  Operating room-based case series and correspondence report on this “dynamic stylet” or “smart bougie” technique, and there is even an RCT.

SGVL or HAVL can be used, though the VL-flex endo technique uniquely leverages the strength of HAVL (obtaining the best view of the glottis) while addressing its key weakness (difficult tube delivery). If VL intubation is unsuccessful, a second operator slides in from the right wielding a flexible endoscope loaded with an endotracheal tube. The VL operator holds the best achievable view (left hand) and utilizes suction (right hand) as the FE operator advances the endoscope to the glottis and into the trachea viewing the mouth directly, then the VL screen, and finally the FE screen as needed.

Airway Strategy with Many Choices

Many modern emergency departments and ICUs have immediate access to VL with hot-swappable SG and HA blades in a variety of sizes, flexible endoscopy, and second generation laryngeal masks that are nearly foolproof to place and designed to easily transmit an ETT.  These new tools can work together in extremely powerful ways, and we haven’t properly updated our airway strategy to take advantage of this. Here is an example of a strategy that does.

The first step is to decide on paralysis vs. breathing; you’ll usually choose RSI, which is usually the right choice, but make sure you know when it isn’t the right choice and the alternatives.

When you’ve decided to move ahead with RSI, the next step is to slow down, think, and prepare for dangerous physiology, optimal oxygenation, and plans A, B, and C. Use a checklist.

Plan A is going to be HAVL or SGVL, and I recommend, unless you’re already excellent with HAVL, that your go-to approach should be SGVL with bougie. When combined with view-optimization maneuvers, you will rarely encounter an airway that cannot be intubated with SGVL+bougie.

When you do encounter such an airway, the best move is not bag-mask ventilation but laryngeal mask ventilation. We’ve known for many years that LMV is both easier to do and more likely to be successful than BMV, and this is even more true now with 2G supraglottics.

Once you have placed an intubating SGA and restored oxygenation, you can go for any Plan A2 you like, but you are now well positioned to intubate through the SGA using flexible endoscopy, which can be done as ventilation continues if you have a swivel adaptor. Alternatively, removing the SGA and performing HAVL will often be successful, especially if you can perform VL-Flex endo, as described above.

Recent years have brought incredible advances in emergency airway management that have made intubation easier to learn and less dangerous. Take a critical look at the devices you stock in your department, what you should stock in your department, and how you can best take advantage of many choices to improve airway outcomes.

Bougie Molding During Laryngoscopy

There is lotsofevidence / that / using / a / bougie will increase your intubation success rate, compared to a styletted endotracheal tube. This is because the bougie is much smaller and easier to maneuver than an ETT, and does not block your view of the target at the last moment, as is often the case with a styletted tube. The Coudé tip allows operators to successfully intubate  grade 3, epiglottis-only views, which means if you are practiced with the bougie and can get a view of the epiglottis, you will be able to intubate.

A less discussed but powerful feature of the bougie is its capacity to be molded; this can be done prior to laryngoscopy (e.g. to conform to the shape of a curved laryngoscope) or during laryngoscopy to allow the bougie to act as a poor man’s flexible endoscope by allowing real-time adjustments to the tip’s trajectory.

This 4-minute video discusses the conventional floppy vs. newer malleable bougies and presents a case where molding a malleable bougie during laryngoscopy turned what could have been a very difficult airway with limited mouth opening into straightforward procedure, even for a junior operator.

There are many manufacturers of floppy and malleable bougies, I have no relationships with any of them.

Airborne Isolation / COVID19 Intubation Checklist

AIIC [pdf]

AIIC [image]

more pearls: make sure cuff is inflated prior to manual ventilation. attach viral filter directly to ETT, if circuit disconnection needed, disconnect circuit on vent side of filter.

References: Zuo 2020, Wax 2020, Weingart 2020, ecuus 1 and 2, Farkas & Thomas 2020

CDC 5 min video on proper donning/doffing, pdf, pulmcrit cheat sheet

 

CDC CV19 Discharge Instructions

LAC DOH CV19 Discharge Instructions

 

Scott’s BVM-on-NIV mask oxygenation setup (6 min vid)

 

Ketamine-Only Breathing Intubation

This 9 minute video demonstrates the strengths and weaknesses of an intubation strategy that relies on dissociation with ketamine.

The essential strength, compared to RSI, is that a breathing technique keeps the patient breathing during laryngoscopy, which transforms the procedure from high-adrenaline to highly controlled. You see in this video that my (fabulous) resident was able to take his time, try different blades, slowly advance and adjust while using view optimization techniques as the patient continued to breathe. This is an extremely powerful way to add safety to the riskiest procedure commonly performed in acute care. We would have been able to carry on with his attempts for longer, had we not been inconvenienced by the arrival of a trauma patient.

Keeping the patient breathing during intubation has a long history in emergency medicine, starting with the brutal and often unsuccessful blind nasal intubation, which, fortunately, is now seldom performed. Many of us learned to do operating room style awake intubation, which relies on thorough local anesthesia using atomized/nebulized/topicalized/regionalized lidocaine, so the patient can remain truly awake and breathing during the procedure. Lidocaine-focused awake intubation is a fabulous technique that requires expertise and equipment not available to all acute care providers, but also–depending on your level of skill–time and patient cooperation. Time and cooperation is something we may not have downstairs or on the side of the road,* but what we lack in time and cooperation, we can make up for in ketamine.

When we use dissociative-dose ketamine to do the heavy lifting in allowing the patient to tolerate laryngoscopy, we obviate much of the needed topicalization expertise/supplies, abbreviate the needed time, and add cooperation with ketamine, cooperation in a vial.  The patient becomes dissociated, breathing but unconscious, which is why I use the term breathing intubation rather than the much more accepted term awake intubation to describe it.

Many patients who receive dissociative-dose ketamine without a paralytic will have some muscle rigidity, and some will develop laryngospasm (which is glottic muscle rigidity).  The patient in this video had some rigidity, which resolved and was not a problem, and this is usually the case. But patients who get ketamine to facilitate laryngoscopy are at much higher risk than procedural sedation patients (who are not having their airway instrumented) to develop laryngospasm and occasionally jaw rigidity, which, together, can cause an immediately dangerous cannot intubate cannot ventilate scenario. Anytime KOBI is being undertaken, a paralytic must be immediately available, ideally drawn up in a syringe, so that the procedure can be converted to a paralyzed technique at any point.

How KOBI fits into our expanding airway toolkit is expertly described by Andrew Merelman and Michael Perlmutter in this WJEM paper.

 

 

 

*some airway experts disagree

 

Postoperative Neck Hematoma

Postoperative neck hematoma is not often discussed in emergency medicine but behaves a lot like neck trauma, because it is neck trauma. These patients should be managed with a high-resource approach and discharged reluctantly, after careful deliberation.

Adapted from Bittner, MD.

The Paper Throat: A Lo-fi, DIY Laryngoscopy Simulator

 

Laryngoscopy involves a series of unnatural movements and hand-eye skills that are not easily learned while simultaneously caring for a dying patient. The Paper Throat is a low fidelity but high yield direct laryngoscopy training tool that is easily assembled and practiced. The hope is that routine use will generate laryngoscopy muscle memory so that training providers can focus on other aspects of airway management when called upon to intubate IRL.

Conceived and produced by Jonas Pologe.

Pulse Ox Lag

Folks put a lot of stock in the pulse oximeter, as they should, because the pulse ox is an awesome feat of engineering and patient safety. But the pulse ox lags.

Here, the inestimable Dr. Jonas Pologe (rhymes with apology) demonstrates pulse ox lag with a breath hold.

Breath hold starts at 0:11, sat is 100%
Saturation starts to drop at 0:48
Breathing commences at 1:25, sat is 82% at this point
Saturation continues to drop until 1:46, then recovers from its nadir of 77%
At 1:58, saturation reaches 100% again

 

Lessons:

1. When the sat is on its way down, the patient is more hypoxic than the pulse ox shows. This is another reason why, when laryngoscopy is not producing an acceptable view of the glottis, you should come out and reestablish ventilation/oxygenation earlier than you think. A more important reason to come out and bag early is described here.

2. When you are reestablishing oxygenation (using a bag mask, laryngeal mask, or endotracheal tube), do not use the pulse ox to judge the adequacy of ventilation, use capnography. That means the capnogram should be attached to the bag mask/LMA/ETT before the first breath is given. If the capnogram is good, ventilation is good, and the pulse ox will catch up, so relax and stop bagging so quickly.