369. Plavix mechanism and indication in ACS / Heparin mechanism and indication in ACS

July 6th, 2008
by reuben in ACS

We need to dose UFH based on the patient’s weight. In addition,
we all should be aware of the most recent ACC/AHA guidelines for NSTE
ACS, which now recommend dosing of UFH at 60 U/kg (maximum, 4000
U) as an intravenous bolus and 12 U/kg per hour (maximum, 1000 U/h) as
a maintenance infusion [2]. Second, be especially meticulous about dosing
with women and with elderly patients.

Melloni C, Alexander KP, Chen AY, et al. Unfractionated heparin dosing
and risk of major bleeding in non-ST-segment elevation acute coronary
syndromes. Am Heart J 2008;156:209-215.

General UFH unfractionated heparin protocol dosing

ICUPocketGuide.pdf (page 48 of 63)

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